The Migrating Motor Complex
The migrating motor complex is a distinct pattern of electromechanical activity observed in gastrointestinal smooth muscle during the periods between meals. It is thought to serve a "housekeeping" role and sweep residual undigested material through the digestive tube. As studied in dogs and man, the cycle recurs every 1.5 to 2 hours and consists of 4 phases:
An increase in gastric, biliary and pancreatic secretion is also seen in conjunction with the motor activity. These secretions probably aid in the cleansing activity of the migrating motor complex and assist in preventing a buildup of bacterial populations in the proximal segments of the digestive tube.
The periodic nature of the migrating motor complex is thought to be controlled from the central nervous system and may be implemented in part by the enteric hormone motilin. Like real housekeeping, the migrating motor complex is readily overridden by "more important" processes - for example, ingestion of food will abolish a migrating motor complex and restore a digestive pattern of motility.
Aside from its apparent importance in maintaining patency of the gastrointestinal lumen, the migrating motor complex has potentially important theraputic and social implications:
|Index of: The Stomach|
Last updated on October 22, 1995
|Author: R. Bowen|
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